The only advantage I could see is fewer misfires. While fantastically good these days when the production levels of .22 RF ammunition are looked at (the billions of rounds made), the fact remains even
in very good RF ammu, the rate of misfire is much higher than that of equal quality center-fire primers.
When I was shooting NRA-Style Bullseye Pistol, I used T-22 for most practice shooting, and while this represented only a very small percentage, after 15 or 20 years of shooting, I had almost a full box of mis-fires sitting on mmy shelf. My plan was to fill the box and then send it to someone I knew at Winchester as a joke. As I got older, I decided it would not be much of a joke telling him it was all from one box, but really, a rather stupid prank, and I ended up scrapping them.